Application of Incident Command Structure to clinical trial management in the academic setting: principles and lessons learned

Author:

Reynolds Penny S.,Michael Mary J.,Spiess Bruce D.

Funder

U.S. Army Medical Research and Materiel Command

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Reference47 articles.

1. Retzios AD. Why do so many phase 3 clinical trials fail? Part 1: the effect of deficient phase 2 trials in therapeutic areas with high failure rates in phase 3 studies. Bay Clinical R&D Services; 2010. p. 46.  http://adrclinresearch.com/Issues_in_Clinical_Research_links/Why%20Pivotal%20Clinical%20Trials%20Fail%20-%20Part%201_v12L_a.pdf .

2. Waring M J, Arrowsmith J, Leach AR, Leeson PD, Mandrell S, Owen RM, Pairaudeau G, Pennie WD, Pickett SD, Wang J, Wallace O, Wei A. An analysis of the attrition of drug candidates from four major pharmaceutical companies. Nature Reviews Drug Discovery. Published online 19 June 2015; doi: 10.1038/nrd4609

3. Buonansegna E, Salomo S, Maier AM, Li-Ying J. Pharmaceutical new product development: why do clinical trials fail? R&D Manag. 2014;44(2):189–202.

4. Smyth RMD, Jacoby A, Altman DG, Gamble C, Williamson PR. The natural history of conducting and reporting clinical trials: interviews with trialists. Trials. 2015;16:16. doi: 10.1186/s13063-014-0536-6 .

5. Calleam Consulting Ltd. Why do projects fail? (blog). International Project Leadership Academy.  http://calleam.com/WTPF .

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