Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial
Author:
Meybohm PatrickORCID, , Lindau Simone, Treskatsch Sascha, Francis Roland, Spies Claudia, Velten Markus, Wittmann Maria, Gueresir Erdem, Stoppe Christian, Kowark Ana, Coburn Mark, Selleng Sixten, Baschin Marcel, Jenichen Gregor, Meersch Melanie, Ermert Thomas, Zarbock Alexander, Kranke Peter, Kredel Markus, Helf Antonia, Laufenberg-Feldmann Rita, Ferner Marion, Wittenmeier Eva, Gürtler Karl-Heinz, Kienbaum Peter, de Abreu Marcel Gama, Sander Michael, Bauer Michael, Seyfried Timo, Gruenewald Matthias, Choorapoikayil Suma, Mueller Markus M., Seifried Erhard, Brosteanu Oana, Bogatsch Holger, Hasenclever Dirk, Zacharowski Kai
Funder
Deutsche Forschungsgemeinschaft
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Medicine (miscellaneous)
Reference32 articles.
1. Carson JL, Guyatt G, Heddle NM, Grossman BJ, Cohn CS, Fung MK, et al. Clinical Practice Guidelines From the AABB: Red Blood Cell Transfusion Thresholds and Storage. JAMA. 2016;316:2025–35. 2. Padhi S, Kemmis-Betty S, Rajesh S, Hill J, Murphy MF, Guideline Development G. Blood transfusion: summary of NICE guidance. BMJ. 2015;351:h5832. 3. Carson JL, Sieber F, Cook DR, Hoover DR, Noveck H, Chaitman BR, et al. Liberal versus restrictive blood transfusion strategy: 3-year survival and cause of death results from the FOCUS randomised controlled trial. Lancet. 2015;385:1183–9. 4. Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med. 1999;340:409–17. 5. Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, et al. Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med. 2014;371:1381–91.
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