Mind the gap? The platform trial as a working environment-Reference-Cited by-同舟云学术

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Mind the gap? The platform trial as a working environment

Published:2019-05-29 Issue:1 Volume:20 Page:
ISSN:1745-6215
Container-title:Trials
language:en
Short-container-title:Trials

Author:

Morrell Liz^ORCID,Hordern Joshua,Brown Louise,Sydes Matthew R.,Amos Claire L.,Kaplan Richard S.,Parmar Mahesh K. B.,Maughan Timothy S.

Funder

Arts and Humanities Research Council

Medical Research Council

Sir Halley Stewart Trust

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Link

http://link.springer.com/content/pdf/10.1186/s13063-019-3377-5.pdf

Reference11 articles.

1. Parmar MK, Sydes MR, Cafferty FH, Choodari-Oskooei B, Langley RE, Brown L, et al. Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols. Clinical Trials. 2017;14(5):451–61.

2. Parmar MKB, Carpenter J, Sydes MR. More multiarm randomised trials of superiority are needed. Lancet. 2014;384(9940):283–4.

3. Woodcock J, LaVange LM. Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both. N Engl J Med. 2017;377(1):62–70.

4. Sydes MR, Parmar MK, Mason MD, Clarke NW, Amos C, Anderson J, et al. Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial. Trials. 2012;13(1):168.

5. Schiavone F, Bathia R, Letchemanan K, Masters L, Amos C, Bara A, et al. This is a Platform Alteration: A Trial Management Perspective on the Operational Aspects of Adaptive and Platform and Umbrella Protocols. Trials. 2019.

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