CONTRACT Study - CONservative TReatment of Appendicitis in Children (feasibility): study protocol for a randomised controlled Trial-Reference-Cited by-同舟云学术

CONTRACT Study - CONservative TReatment of Appendicitis in Children (feasibility): study protocol for a randomised controlled Trial

Published:2018-03-02 Issue:1 Volume:19 Page:
ISSN:1745-6215
Container-title:Trials
language:en
Short-container-title:Trials

Author:

Hutchings Natalie^ORCID,Wood Wendy,Reading Isabel,Walker Erin,Blazeby Jane M.,van’t Hoff William,Young Bridget,Crawley Esther M.,Eaton Simon,Chorozoglou Maria,Sherratt Frances C.,Beasant Lucy,Corbett Harriet,Stanton Michael P.,Grist Simon,Dixon Elizabeth,Hall Nigel J.

Funder

Health Technology Assessment Programme

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Link

http://link.springer.com/content/pdf/10.1186/s13063-018-2520-z.pdf

Reference35 articles.

1. St Peter SD, et al. Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomized trial. J Pediatr Surg. 2008;43(6):981–5.

2. Minneci PC, et al. Effectiveness of patient choice in nonoperative vs surgical management of pediatric uncomplicated acute appendicitis. JAMA Surg. 2016;151(5):408–15.

3. Varadhan KK, Neal KR, Lobo DN. Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials. BMJ. 2012;344:e2156.