Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial-Reference-Cited by-同舟云学术

Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial

Published:2015-05-16 Issue:1 Volume:16 Page:
ISSN:1745-6215
Container-title:Trials
language:en
Short-container-title:Trials

Author:

Casarin Annalisa,McAuley Daniel F,Alce Timothy M,Zhao Xiaobei,Ely E Wesley,Jackson Jim C,McDowell Cliona,Agus Ashley,Murphy Lynn,Page Valerie J

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Link

http://link.springer.com/content/pdf/10.1186/s13063-015-0731-0.pdf

Reference35 articles.

1. Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004;291(14):1753–62.

2. Xie Z, Dong Y, Maeda U, Moir R, Inouye SK, Culley DJ, et al. Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol. 2006;61A:1300–6.

3. Simone MJ, Tan ZS. The role of inflammation in the pathogenesis of delirium and dementia in older adults: a review. CNS Neurosci Ther. 2011;17:506–13.

4. Cunningham C. Systemic inflammation and delirium: important co-factors in the progression of dementia. Biochem Soc Trans. 2011;39:945–53.

5. Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, et al. Long-term cognitive impairment after critical illness. N Engl J Med. 2013;369(14):1306–16.

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Update on Statin Treatment in Patients with Neuropsychiatric Disorders;Life;2021-12-08

2. The Role of Statins in the Management of Delirium: Recent Advances;CNS & Neurological Disorders - Drug Targets;2021-10-26

3. Efficacy evaluation of exercise as an augmentation strategy to brief behavioral activation treatment for depression: a randomized pilot trial;Cognitive Behaviour Therapy;2019-07-30

4. Evidence Base Update of Psychosocial Treatments for Self-Injurious Thoughts and Behaviors in Youth;Journal of Clinical Child & Adolescent Psychology;2019-05-02

5. Making cold malignant pleural effusions hot: driving novel immunotherapies;OncoImmunology;2019-01-22