A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers

Author:

Green Francis H. Y.,Leigh Richard,Fadayomi Morenike,Lalli Gurkeet,Chiu Andrea,Shrestha Grishma,ElShahat Sharif G.,Nelson David Evan,El Mays Tamer Y.,Pieron Cora A.,Dennis John H.

Funder

Alberta Lung Association

Alberta Innovates - Health Solutions

SolAeroMed Inc

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Reference35 articles.

1. Global Asthma Network. Global asthma report 2014. http://www.globalasthmareport.org/ . Accessed 3 May 2016.

2. World Health Organization. Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach. 2007. http://www.who.int/gard/publications/GARD%20Book%202007.pdf?ua=1 . Accessed 26 Jan 2016.

3. Statistics Canada. Asthma. 2011. http://www.statcan.gc.ca/pub/82-625-x/2012001/article/11658-eng.htm . Accessed 26 Jan 2016.

4. Public Health Agency of Canada. Fast facts about asthma: data compiled from the 2011 survey on living with chronic diseases in Canada. 2011. http://www.phac-aspc.gc.ca/cd-mc/crd-mrc/assets/pdf/asthma_fs_asthme-eng.pdf . Accessed 3 May Jan 2016.

5. Ismaila AS, Sayani AP, Marin M, Su Z. Clinical, economic, and humanistic burden of asthma in Canada: a systematic review. BMC Pulm Med. 2013;13:70.

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