A single-blind, dose-escalation, phase I study of high-fluence light-emitting diode-red light on Caucasian non-Hispanic skin: study protocol for a randomized controlled trial

Author:

Wang Erica B.,Kaur Ramanjot,Nguyen Julie,Ho Derek,Austin Evan,Maverakis Emanual,Li Chin-Shang,Hwang Samuel T.,Isseroff R. Rivkah,Jagdeo Jared

Funder

National Institute of General Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Reference41 articles.

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2. Austin E, Huang A, Adar T, Wang E, Jagdeo J. Electronic device generated light increases reactive oxygen species in human fibroblasts. Lasers Surg Med. 2018. https://doi.org/10.1002/lsm.22794 [Epub ahead of print].

3. Porges SB, Kaidbey KH, Grove GL. Quantification of visible light-induced melanogenesis in human skin. Photodermatol. 1988;5:197–200.

4. Soleymani T, Cohen DE, Folan LM, Okereke UR, Elbuluk N, Soter NA. Disparity in Cutaneous Pigmentary Response to LED vs Halogen Incandescent Visible Light: Results from a Single Center, Investigational Clinical Trial Determining a Minimal Pigmentary Visible Light Dose. J Drugs Dermatol. 2017;16:1105–10.

5. Sklar LR, Almutawa F, Lim HW, Hamzavi I. Effects of ultraviolet radiation, visible light, and infrared radiation on erythema and pigmentation: a review. Photochem Photobiol Sci. 2013;12:54–64.

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