A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])-Reference-Cited by-同舟云学术

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A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])

Published:2017-07-17 Issue:1 Volume:18 Page:
ISSN:1745-6215
Container-title:Trials
language:en
Short-container-title:Trials

Author:

Mahmood Abda^ORCID,Roberts Ian,Shakur Haleema

Funder

United Kingdom Department for International Development/Medical Research Council/Wellcome Trust through the Joint Global Health Trials Scheme

National Institute for Health Research, Health Technology Assessment

London School of Hygiene and Tropical Medicine

The JP Moulton Charitable Foundation

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Link

http://link.springer.com/content/pdf/10.1186/s13063-017-2073-6.pdf

Reference77 articles.

1. Hyder AA, Wunderlich CA, Puvanachandra P, Gururaj G, Kobusingye OC. The impact of traumatic brain injuries: a global perspective. NeuroRehabilitation. 2007;22(5):341–53.

2. Hancock CBHJ. The global burden of traumatic brain injury: preliminary results from the Global Burden of Disease Project. Inj Prev. 2010;16:A17.

3. Bruns Jr J, Hauser WA. The epidemiology of traumatic brain injury: a review. Epilepsia. 2003;44 Suppl 10:2–10.

4. Berkner J, Mannix R, Qiu J. Clinical traumatic brain injury in the preclinical setting. Methods Mol Biol. 2016;1462:11–28.

5. Bunch J, Jennifer H. Information and Resources Column. TBI challenge 4, No. 2. Alexandria: BIA; 2000.

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