Design and implementation of a large and complex trial in emergency medical services

Author:

Robinson Maria J.ORCID, ,Taylor Jodi,Brett Stephen J.,Nolan Jerry P.,Thomas Matthew,Reeves Barnaby C.,Rogers Chris A.,Voss Sarah,Clout Madeleine,Benger Jonathan R.

Funder

Health Technology Assessment Programme

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Reference22 articles.

1. Taylor J, Black S, Brett SJ, Kirby K, Nolan JP, Reeves BC, et al. Design and implementation of the AIRWAYS-2 trial: a multi-centre cluster randomised controlled trial of the clinical and cost effectiveness of the i-gel supraglottic airway device versus tracheal intubation in the initial airway management of out of hospital cardiac arrest. Resuscitation. 2016;109:25–32. https://doi.org/10.1016/j.resuscitation.2016.09.016 .

2. Benger JR, Kirby K, Black S, Brett SJ, Clout M, Lazaroo MJ, Nolan JP, Reeves BC, Robinson M, Scott LJ, Smartt H. Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome: the AIRWAYS-2 randomized clinical trial. JAMA. 2018;320(8):779–91.

3. Chamberlain D, Cummins RO, Abramson N, Allen M, Baskett P, Becker L, et al. Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the ‘Utstein style’. Resuscitation. 22(1):1–26. https://doi.org/10.1016/0300-9572(91)90061-3 .

4. Hawkes C, Booth S, Ji C, Brace-McDonnell SJ, Whittington A, Mapstone J, et al. Epidemiology and outcomes from out-of-hospital cardiac arrests in England. Resuscitation. 2017;110:133–40. https://doi.org/10.1016/j.resuscitation.2016.10.030 .

5. Nichol G, Brown SP, Perkins GD, Kim F, et al. What change in outcomes after cardiac arrest is necessary to change practice? Results of an international survey. Resuscitation. 2016;107:115–20. https://doi.org/10.1016/j.resuscitation.2016.08.004 .

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