Safety and efficacy of intravenous infusion of allogeneic cryopreserved mesenchymal stem cells for treatment of chronic kidney disease in cats: results of three sequential pilot studies

Author:

Quimby Jessica M,Webb Tracy L,Habenicht Lauren M,Dow Steven W

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Medicine,Medicine (miscellaneous)

Reference40 articles.

1. DiBartola SP, Rutgers HC, Zack PM, Tarr MJ: Clinicopathologic findings associated with chronic renal disease in cats: 74 cases (1973–1984). J Am Vet Med Assoc. 1987, 190: 1196-1202.

2. Chakrabarti S, Syme HM, Brown CA, Elliott J: Histomorphometry of feline chronic kidney disease and correlation with markers of renal dysfunction. Vet Pathol. 2013, 50: 147-155. 10.1177/0300985812453176.

3. Lee SR, Lee SH, Moon JY, Park JY, Lee D, Lim SJ, Jeong KH, Park JK, Lee TW, Ihm CG: Repeated administration of bone marrow-derived mesenchymal stem cells improved the protective effects on a remnant kidney model. Ren Fail. 2010, 32: 840-848. 10.3109/0886022X.2010.494803.

4. Semedo P, Correa-Costa M, Antonio Cenedeze M, Maria- Avancini-Costa-Malheiros D, Antonia-dos-Reis M, Shimizu MH, Seguro AC, Pacheco-Silva A, Saraiva-Camara NO: Mesenchymal stem cells attenuate renal fibrosis through immune modulation and remodeling properties in a rat remnant kidney model. Stem Cells. 2009, 27: 3063-3073.

5. Villanueva S, Ewertz E, Carrión F, Tapia A, Vergara C, Céspedes C, Sáez PJ, Luz P, Irarrázabal C, Carreño JE, Figueroa F, Vio CP: Mesenchymal stem cell injection ameliorates chronic renal failure in a rat model. Clin Sci (Lond). 2011, 121: 489-499. 10.1042/CS20110108.

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