Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
Author:
Funder
Ministero dellIstruzione, dellUniversità e della Ricerca
Ministero della Salute
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://link.springer.com/content/pdf/10.1186/s40064-016-3091-7.pdf
Reference38 articles.
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2. Broers J, Ramaekers F (2006) Nuclear lamins: laminopathies and their role in premature ageing. Physiol Rev 86:967–1008. doi: 10.1152/physrev.00047.2005
3. Caron M, Auclair M, Donadille B et al (2007) Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence. Cell Death Differ 14:1759–1767. doi: 10.1038/sj.cdd.4402197
4. Coppe J-P, Desprez P-Y, Krtolica A, Campisi J (2010) The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 5:99–118. doi: 10.1146/annurev-pathol-121808-102144
5. Crowe EP, Nacarelli T, Bitto A et al (2014) Detecting senescence: methods and approaches. In: Noguchi E, Gadaleta MC (eds) Cell cycle control. Springer, New York, NY, pp 425–445
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