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Strategy to develop a MAO-A-resistant 5-hydroxy-l-[β-11C]tryptophan isotopologue based on deuterium kinetic isotope effects

  • Published:2014-11-30 Issue:1 Volume:4 Page:
  • ISSN:2191-219X
  • Container-title:EJNMMI Research
  • language:en
  • Short-container-title:EJNMMI Res

Author:

Eriksson Jonas,Åberg Ola,Selvaraju Ram Kumar,Antoni Gunnar,Johansson Lars,Eriksson Olof

Publisher

Springer Science and Business Media LLC

Subject

Radiology, Nuclear Medicine and imaging

Reference13 articles.

1. Orlefors H, Sundin A, Garske U, Juhlin C, Oberg K, Skogseid B, Langstrom B, Bergstrom M, Eriksson B: Whole-body 11C-5-hydroxytryptophan positron emission tomography as a universal imaging technique for neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and computed tomography. J Clin Endocrinol Metab 2005, 90: 3392–3400. 10.1210/jc.2004-1938

2. Di Gialleonardo V, Signore A, Scheerstra EA, Visser AK, Van Waarde A, Dierckx RA, De Vries EF: 11C-hydroxytryptophan uptake and metabolism in endocrine and exocrine pancreas. J Nucl Med 2012, 53: 1755–1763. 10.2967/jnumed.112.104117

3. Eriksson O, Selvaraju R, Johansson L, Eriksson JW, Sundin A, Antoni G, Sörensen J, Eriksson B, Korsgren O: Quantitative imaging of serotonergic biosynthesis and degradation in the endocrine pancreas. J Nucl Med 2014, 55: 460–465. 10.2967/jnumed.113.125187

4. Eriksson O, Espes D, Selvaraju RK, Jansson E, Antoni G, Sörensen J, Lubberink M, Biglarnia A, Eriksson JW, Sundin A, Ahlström H, Eriksson B, Johansson L, Carlsson PO, Korsgren O: Positron emission tomography ligand [11C]5-hydroxy-tryptophan can be used as a surrogate marker for the human endocrine pancreas. Diabetes 2014, 63(10):3428–3437. 10.2337/db13-1877

5. Orlefors H, Sundin A, Lu L, Oberg K, Långström B, Eriksson B, Bergström M: Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography. Eur J Nucl Med Mol Imaging 2006, 33: 60–65. 10.1007/s00259-005-1891-z

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