Author:
Conca Francesca,Esposito Valentina,Rundo Francesco,Quaranta Davide,Muscio Cristina,Manenti Rosa,Caruso Giulia,Lucca Ugo,Galbussera Alessia Antonella,Di Tella Sonia,Baglio Francesca,L’Abbate Federica,Canu Elisa,Catania Valentina,Filippi Massimo,Mattavelli Giulia,Poletti Barbara,Silani Vincenzo,Lodi Raffaele,De Matteis Maddalena,Stanzani Maserati Michelangelo,Arighi Andrea,Rotondo Emanuela,Tanzilli Antonio,Pace Andrea,Garramone Federica,Cavaliere Carlo,Pardini Matteo,Rizzetto Cristiano,Sorbi Sandro,Perri Roberta,Tiraboschi Pietro,Canessa Nicola,Cotelli Maria,Ferri Raffaele,Weintraub Sandra,Marra Camillo,Tagliavini Fabrizio,Catricalà Eleonora,Cappa Stefano Francesco
Abstract
Abstract
Background
Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer’s disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to solve this issue.
Methods
Following the initiative of the University of Washington’s National Alzheimer’s Coordinating Center (NACC), we presented the Italian adaptation of the Neuropsychological Test Battery of the Uniform Data Set (I-UDSNB). We collected data from 433 healthy Italian individuals and employed regression models to evaluate the impact of demographic variables on the performance, deriving the reference norms.
Results
Higher education and lower age were associated with a better performance in the majority of tests, while sex affected only fluency tests and Digit Span Forward.
Conclusions
The I-UDSNB offers a valuable and harmonized tool for neuropsychological testing in Italy, to be used in clinical and research settings.
Publisher
Springer Science and Business Media LLC
Subject
Cognitive Neuroscience,Neurology (clinical),Neurology