Genome and proteome screening of Onchocerca volvulus reveal putative vaccine candidates
Author:
Funder
Africa Centre of Excellence for Neglected Tropical Diseases and Forensic Biotechnology
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
https://link.springer.com/content/pdf/10.1186/s43556-021-00062-z.pdf
Reference5 articles.
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2. Sanches RCO, Tiwari S, Ferreira LCG, Oliveira FM, Lopes MD, Passos MJF, et al. Immunoinformatics design of multi-epitope peptide-based vaccine against schistosoma mansoni using transmembrane proteins as a target. Front Immunol. 2021;12(621706):1–16. https://doi.org/10.3389/fimmu.2021.621706.
3. Godel C, Kumar S, Koutsovoulos G, Ludin P, Nilsson D, Comandatore F, et al. The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets. FASEB J. 2012;26(11):4650–61. https://doi.org/10.1096/fj.12-205096.
4. McCarthy JS, Wieseman M, Tropea J, Kaslow D, Abraham D, Lustigman S, et al. Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphoshate aldolase as a target for a protective immune response in humans. Infect Immun. 2002;70(2):851–8. https://doi.org/10.1128/IAI.70.2.851-858.2002.
5. Wu Y, Preston G, Bianco AE. Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi. Mol Biochem Parasitol. 2008;161(1):55–62. https://doi.org/10.1016/j.molbiopara.2008.06.007.
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1. Potential of Onchocerca ochengi inosine-5′-monophosphate dehydrogenase (IMPDH) and guanosine-5′-monophosphate oxidoreductase (GMPR) as druggable and vaccine candidates: immunoinformatics screening;Journal of Biomolecular Structure and Dynamics;2023-03-03
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