Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - the importance of quality control and a standard reporting framework

Author:

Jacques David A,Guss Jules Mitchell,Trewhella Jill

Abstract

Abstract Small-angle scattering is becoming an increasingly popular tool for the study of bio-molecular structures in solution. The large number of publications with 3D-structural models generated from small-angle solution scattering data has led to a growing consensus for the need to establish a standard reporting framework for their publication. The International Union of Crystallography recently established a set of guidelines for the necessary information required for the publication of such structural models. Here we describe the rationale for these guidelines and the importance of standardising the way in which small-angle scattering data from bio-molecules and associated structural interpretations are reported.

Publisher

Springer Science and Business Media LLC

Subject

Structural Biology

Cited by 20 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. 2023 update of template tables for reporting biomolecular structural modelling of small-angle scattering data;Acta Crystallographica Section D Structural Biology;2023-02-01

2. Towards the standardized presentation and publication of small-angle scattering data from biomolecules in solution;Acta Crystallographica Section D Structural Biology;2023-02-01

3. Data quality assurance, model validation, and data sharing for biomolecular structures from small-angle scattering;Small Angle Scattering Part B: Methods for Structural Interpretation;2023

4. Planning, executing and assessing the validity of SANS contrast variation experiments;Small Angle Scattering Part A: Methods for Structural Investigation;2022

5. Contrast variation SAXS: Sample preparation protocols, experimental procedures, and data analysis;Small Angle Scattering Part A: Methods for Structural Investigation;2022

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