Association between male sex hormones and tramadol abuse

Author:

Abdel-Moneim Wafaa Mohamed,Fawzy Mohammed,Mohammed Sarah Abdelsamee,Abdellah Nora Zeidan

Abstract

Abstract Background Tramadol dependence is prevalent across Egypt. The allegation that it can improve sexual function is the main reason for its popularity among young men. This study aims to determine the serum level of testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) in tramadol abusers. Results Serum testosterone (5.18 ± 1.95) and LH (7.79 ± 1.63) of abusers showed highly significant lower levels than control subjects, while FSH showed no significant difference between abusers and controls. There was no significant difference of hormonal levels in subjects according to the duration of abuse and dose of tramadol. Conclusions The results indicate that tramadol abuse causes a pronounced lowering of testosterone and LH levels that is not correlated to the duration of abuse and dose of tramadol.

Funder

Faculty of Medicine, Assiut University grant office

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health

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