Effect of one-month treatment with methylphenidate on salivary cortisol level of attention deficit hyperactivity disorder children-Reference-Cited by-同舟云学术

Effect of one-month treatment with methylphenidate on salivary cortisol level of attention deficit hyperactivity disorder children

Published:2021-03-02 Issue:1 Volume:28 Page:
ISSN:2090-5416
Container-title:Middle East Current Psychiatry
language:en
Short-container-title:Middle East Curr Psychiatry

Author:

Kholif Esraa Yahia^ORCID,Awad Salwa Mohamed,Attia Nasr Mohamed,Tawhid Ziyad Essam,Elwasify Mahmoud

Abstract

Abstract Background Attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychological disorders that affects children, adolescents, and adults. Dysfunction of the hypothalamic-pituitary-adrenal axis (HPA) has been implicated in its pathophysiology. So, this study aimed to compare the salivary cortisol level between ADHD children and healthy children. It also compared the salivary cortisol level of ADHD children before treatment and 1 month after treatment with methylphenidate. Results This study showed that there was a statistically significant decrease in salivary cortisol level of the ADHD group, specifically hyperactive/impulsive subtype compared to the control group. Furthermore, it showed a statistically significant increase of salivary cortisol level after treatment compared to before treatment in the ADHD group. Conclusions HPA axis dysfunction may be related to the pathophysiology of ADHD, specifically hyperactive/impulsive subtype. Methylphenidate positively affects the HPA axis of ADHD children.

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health

Link

http://link.springer.com/content/pdf/10.1186/s43045-021-00091-y.pdf

Reference25 articles.

1. Association A (1994) Diagnostic and statistical manual of mental disorders, 4th edn. Am Psych Assoc, Washington DC, pp 6294–6304

2. Breton J, Bergeron L, Valla J, Berthiaume C, Gaudet N, Lambert J, Lépine S (1999) Quebec child mental health survey: prevalence of DSM-III-R mental health disorders. J Child Psychol Psych. 40:375–384

3. Chae P, Jung H, Noh K (2001) Attention deficit hyperactivity disorder in Korean juvenile delinquents. Adol. 36:707

4. No Authors Listed (2003,2005) Control CFD and prevention, mental health in the United States. Prevalence of diagnosis and medication treatment for attention-deficit/hyperactivity disorder-United States. Morb and mort week repo.54:842.

5. Parker H (2005) The ADHD handbook for schools: effective strategies for identifying and teaching students with attention-deficit/hyperactivity disorder. Special Press/ADD Warehouse, vol 43, p 48

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Moderating effects of impulsivity and morning cortisol on the genotype‐phenotype relationship of attention deficit hyperactivity disorder in young adults;Stress and Health;2023-08-25

2. Physical Exercise to Treat ADHD;Clinical Handbook of ADHD Assessment and Treatment Across the Lifespan;2023