Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan

Author:

Rehman Irshad-ur,Idrees Muhammad,Ali Muhammad,Ali Liaqat,Butt Sadia,Hussain Abrar,Akbar Haji,Afzal Samia

Abstract

Abstract Background Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan. Findings The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six other HCV genotype 3a full length sequences from different regions of the world by using statistical methods of phylogenetic analysis. Conclusion The nucleotide difference of these seven sequences shows that HCV genotype 3a of phylogenetically distinct origin is circulating in Pakistan.

Publisher

Springer Science and Business Media LLC

Subject

Molecular Medicine,Immunology,Immunology and Allergy,Biotechnology

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