Author:
Zhou Minyu,Cao Ke,Huang Hui,Luo Xiaojuan,Wang Ying,Ma Weike,Lv Zhiyue
Abstract
Abstract
Background
Myiasis is caused by dipterous larvae, and rarely affects the mouth. Diagnosis by traditional means is easy to be confused with other similar species. Here, we report a case of oral myiasis, in a 5-month-old infant who was diagnosed by morphological examination and molecular biological methods.
Case presentation
A 5-month old infant with acute myeloid leukemia was admitted due to recurrent skin masses for more than 4 months. The infant had lip swelling, which prevented him from closing the mouth and membranes were present in his mouth and there were also oral ulcers and erosions. Ten maggots were found in the mouth and one in the ear canal with pus flowing out and were confirmed as the third stage larvae of Sarcophaga ruficornis by morphological examination and a comparison of sequence of cytochrome oxidase subunit 1 (COX1) gene. After removal of the maggots and chemotherapy, the infant ’s condition was gradually improved.
Conclusions
To the best of our our knowledge, this is the first neonatal oral myiasis case reported in China and its diagnosis requires a high index of suspicion. Microscopy combined with specific DNA sequence analysis is an effective technological tool to provide rapid diagnoses of the larva specimen and cases of rare diseases, as illustrated in the current case.
Funder
National Natural Science Foundation of China
National Parasitic Resources Center of China
Science and Technology Planning Project of Guangdong Province
Natural Science Foundation of Guangdong Province
Open Foundation of Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Medical University
111 Project
Key Research and Development Program of Hainan Province
Major Science and Technology Project of Hainan Province
Publisher
Springer Science and Business Media LLC
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