Occurrence of septuple and elevated Pfdhfr-Pfdhps quintuple mutations in a general population threatens the use of sulfadoxine-pyrimethamine for malaria prevention during pregnancy in eastern-coast of Tanzania
Author:
Funder
Swedish International Development Cooperation Agency (Sida), Sweden
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases
Link
http://link.springer.com/content/pdf/10.1186/s12879-020-05253-7.pdf
Reference27 articles.
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2. WHO. Global report on antimalarial drug efficacy and drug resistance: 2000–2010, vol. 115: Who; 2010.
3. Mohammed A, et al. Trends in chloroquine resistance marker , Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. Malar J. 2013;12(1):1.
4. NDEJEMBI M, et al. Therapeutic efficacy of Sulfadoxine-Pyrimethamine and prevalence of resistance markers in Tanzania Prior to revision of malaria treatment policy: Plasmodium falciparum Dihydrofolate Reductase and Dihydropteroate synthase mutations in monitoring in vivo re. Am J Trop Med Hyg. 2018;71(6):696–702.
5. Mubyazi GM, Gonzalez-Block MA. Research influence on antimalarial drug policy change in Tanzania: case study of replacing chloroquine with sulfadoxine-pyrimethamine as the first-line drug. Malar J. 2005;4:1–13.
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1. Effectiveness of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine in Pregnancy: Low Coverage and High Prevalence of Plasmodium falciparum dhfr-dhps Quintuple Mutants as Major Challenges in Douala, an Urban Setting in Cameroon;Pathogens;2023-06-19
2. Molecular Determinants of Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum Isolates from Central Africa between 2016 and 2021: Wide Geographic Spread of Highly Mutated Pfdhfr and Pfdhps Alleles;Microbiology Spectrum;2022-10-26
3. The prevalence of molecular markers of resistance to sulfadoxine-pyrimethamine among pregnant women at first antenatal clinic attendance and delivery in the forest-savannah area of Ghana;PLOS ONE;2022-08-08
4. Artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers;Malaria Journal;2022-04-27
5. Effectiveness of Intermittent Preventive Treatment With Dihydroartemisinin‐Piperaqunine Against Malaria in Pregnancy in Tanzania: A Randomized Controlled Trial;Clinical Pharmacology & Therapeutics;2021-06-17
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