A case of Henoch-Schönlein purpura associated with scrub typhus

Author:

Im Jae Hyoung,Choi Suk Jin,Chung Moon-Hyun,Lee Seung Yun,Park Young Kyoung,Kwon Hea Yoon,Baek Ji Hyeon,Lee Jin-Soo

Abstract

Abstract Background Henoch-Schönlein purpura (HSP) may be caused by several allergens. However, to date, HSP caused by Orientia tsutsugamushi has not been reported. Here, we report an unusual rash with features of HSP caused by Orientia tsutsugamushi. Case presentation A man visited a tertiary hospital with bilateral symmetrical purpura and fever. He presented with an eschar in the left popliteal fossa and proteinuria. He was diagnosed with tsutsugamushi disease by indirect fluorescent antibody and positive polymerase chain reaction tests. Purpura biopsy demonstrated a feature of leukocytoclastic vasculitis and IgA deposition in dermal vessels, indicative of HSP. Conclusions When examining patients with unique rashes, such as in this case, we suggest investigating out-door activities and evidence of mite bites. Furthermore, differential diagnosis of tsutsugamushi disease should be considered when necessary.

Funder

National Research Foundation of Korea

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases

Reference17 articles.

1. Bennett JE, Dolin R, Blaser MJ. Principles and practice of infectious diseases, vol. 1: Elsevier Health Sciences; 2014.

2. Luce-Fedrow A, Lehman M, Kelly D, Mullins K, Maina A, Stewart R, Ge H, John H, Jiang J, Richards AJTm et al: A review of scrub typhus (Orientia tsutsugamushi and related organisms): then, now, and tomorrow. 2018, 3(1):8.

3. Otterdal K, Janardhanan J, Astrup E, Ueland T, Prakash JA, Lekva T, Abraham O, Thomas K, Damås JK, Mathews P. Increased endothelial and macrophage markers are associated with disease severity and mortality in scrub typhus. J Infect. 2014;69(5):462–9.

4. Saulsbury F. Epidemiology of Henoch-Schonlein purpura. Cleve Clin J Med. 2002;69:SII-87.

5. Park S-H, Hwang K-J, Chu H, Park M-Y. Serological detection of Lyme borreliosis agents in patients from Korea, 2005–2009. Osong Public Health Res Perspect. 2011;2(1):29–33.

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