Enterovirus D68 in a 6-year-old acute flaccid myelitis case in China, 2018: a case report
-
Published:2020-02-11
Issue:1
Volume:20
Page:
-
ISSN:1471-2334
-
Container-title:BMC Infectious Diseases
-
language:en
-
Short-container-title:BMC Infect Dis
Author:
Wang Xiaoli,Zhang Pengfei,Li Jie,Chu Yanhui,Li Zheng,Yang Yang,Li Fu,Cui Shujuan,Huo Da,Wang Yu,Wang Quanyi
Abstract
Abstract
Background
Acute flaccid myelitis (AFM) are reported to be associated with enterovirus D68 infection. Though an increasing number of AFM cases were reported with EV-D68 infection in the US, few such cases have been found in China.
Case presentation
A 6-year-old boy presented with acute flaccid myelitis (AFM) involving left arm after fever and respiratory symptoms for 6 days. Computed Tomography (CT) revealed inflammation in both lungs and magnetic resonance imaging (MRI) of the brain and spine showed swelling in the left frontal lobe and brain stem. The patient was diagnosed with meningomyelitis. EV-D68 was detected from pharyngeal samples 36 days after the onset of the disease.
Conclusion
We report the first EV-D68 infection in case of AFM in mainland China. AFM surveillance systems is recommended to be established in China to guide diagnosis, case reporting, and specimen collection and testing for better understanding its etiologies.
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases
Reference15 articles.
1. Midgley CM, Watson JT, Nix WA, Curns AT, Rogers SL, Brown BA, Conover C, Dominguez SR, Feikin DR, Gray S, Hassan F, Hoferka S, Jackson MA, Johnson D, Leshem E, Miller L, Nichols JB, Nyquist AC, Obringer E, Patel A, Patel M, Rha B, Schneider E, Schuster JE, Selvarangan R, Seward JF, Turabelidze G, Oberste MS, Pallansch MA, Gerber SI. EV-D68 Working Group. Severe respiratory illness associated with a nationwide outbreak of enterovirus D68 in the USA (2014): a descriptive epidemiological investigation. Lancet Respir Med. 2015;3:879–87. 2. Drews SJ, Simmonds K, Usman HR, Yee K, Fathima S, Tipples G, Tellier R, Pabbaraju K, Wong S, Talbot J. Characterization of enterovirus activity, including that of enterovirus D68, in pediatric patients in Alberta, Canada, in 2014. J Clin Microbiol. 2015;53:1042–5. 3. Bal A, Schuffenecker I, Casalegno JS, Josset L, Valette M, Armand N, Dhondt PB, Escuret V, Lina B. Enterovirus D68 nosocomial outbreak in elderly people, France, 2014. Clin Microbiol Infect. 2015;21:e61–2. 4. Zhang T, Ren L, Luo M, Li A, Gong C, Chen M, Yu X, Wu J, Deng Y, Huang F. Enterovirus D68-associated severe pneumonia, China, 2014. Emerg Infect Dis. 2015;21:916–8. 5. Ayscue P, Van Haren K, Sheriff H, Waubant E, Waldron P, Yagi S, Yen C, Clayton A, Padilla T, Pan C, Reichel J, Harriman K, Watt J, Sejvar J, Nix WA, Feikin D, Glaser C. Centers for Disease Control and Prevention (CDC). Acute flaccid paralysis with anterior myelitis-California, June 2012-June 2014. MMWR Morb Mortal Wkly Rep. 2014;63:903–6.
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|