Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells
Author:
Funder
Korea University Grant
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://link.springer.com/content/pdf/10.1186/s12860-017-0130-3.pdf
Reference33 articles.
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3. Robertson KD. DNA methylation, methyltransferases, and cancer. Oncogene. 2001;20:3139–55.
4. Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet. 2000;24:88–91.
5. Liu X, Gao Q, Li P, Zhao Q, Zhang J, Li J, et al. UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9. Nat Commun. 2013;4:1563.
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