Angioarchitectural features amongst patients with unruptured brain arteriovenous malformations presenting with headache: findings from a single center retrospective review of 76 patients
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Published:2021-10-09
Issue:1
Volume:22
Page:
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ISSN:1129-2369
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Container-title:The Journal of Headache and Pain
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language:en
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Short-container-title:J Headache Pain
Author:
Africk Benjamin N,Heiferman Daniel M,Wozniak Amy W,Behzadi Faraz,Ballard Matthew S,Chazaro Joshua M,Zsigray Brandon M,Shanker Rachyl M,Reynolds Matthew R,Anderson Douglas E,Serrone Joseph C
Abstract
Abstract
Background
Brain arteriovenous malformations (AVMs) consist of abnormal connections between arteries and veins via an interposing nidus. While hemorrhage is the most common presentation, unruptured AVMs can present with headaches, seizures, neurological deficits, or be found incidentally. It remains unclear as to what AVM characteristics contribute to pain generation amongst unruptured AVM patients with headaches.
Methods
To assess this relationship, the current study evaluates angiographic and clinical features amongst patients with unruptured brain AVMs presenting with headache. Loyola University Medical Center medical records were queried for diagnostic codes corresponding to AVMs. In patients with unruptured AVMs, we analyzed the correlation between the presenting symptom of headache and various demographic and angiographic features.
Results
Of the 144 AVMs treated at our institution between 1980 and 2017, 76 were unruptured and had sufficient clinical data available. Twenty-three presented with headaches, while 53 patients had other presenting symptoms. Patients presenting with headache were less likely to have venous stenosis compared to those with a non-headache presentation (13 % vs. 36 %, p = 0.044).
Conclusions
Our study suggests that the absence of venous stenosis may contribute to headache symptomatology. This serves as a basis for further study of correlations between AVM angioarchitecture and symptomatology to direct headache management in AVM patients.
Publisher
Springer Science and Business Media LLC
Subject
Anesthesiology and Pain Medicine,Neurology (clinical),General Medicine
Reference26 articles.
1. Lawton MT, Rutledge WC, Kim H, Stapf C, Whitehead KJ, Li DY, Krings T, terBrugge K, Kondziolka D, Morgan MK, Moon K, Spetzler RF (2015) Brain arteriovenous malformations, Nature reviews. Disease primers 1:15008 2. Sahlein DH, Mora P, Becske T, Huang P, Jafar JJ, Connolly ES, Nelson PK (2014) Features predictive of brain arteriovenous malformation hemorrhage: extrapolation to a physiologic model. Stroke 45(7):1964–1970 3. Gross BA, Du R, Natural history of cerebral arteriovenous malformations: a meta-analysis, Journal of neurosurgery 118(2) (2013) 437 – 43 4. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG (2009) Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 42(2):377–381 5. Atkinson RP, Awad IA, Batjer HH, Dowd CF, Furlan A, Giannotta SL, Gomez CR, Gress D, Hademenos G, Halbach V, Hemphill JC, Higashida RT, Hopkins LN, Horowitz MB, Johnston SC, Lawton MW, McDermott MW, Malek AM, Mohr JP, Qureshi AI, Riina H, Smith WS, Pile-Spellman J, Spetzler RF, Tomsick TA, Young WL (2001) Reporting terminology for brain arteriovenous malformation clinical and radiographic features for use in clinical trials. Stroke 32(6):1430–1442
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