Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia-Reference-Cited by-同舟云学术

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Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia

Published:2016-01-18 Issue:1 Volume:13 Page:
ISSN:1742-2094
Container-title:Journal of Neuroinflammation
language:en
Short-container-title:J Neuroinflammation

Author:

de Oliveira Antonio Carlos Pinheiro,Yousif Nizar M.,Bhatia Harsharan Singh,Hermanek Julia,Huell Michael,Fiebich Bernd L.

Funder

Alzheimer Forschung initiative e.V (AFI)

State Law on Graduate Funding (LGFG-IGA, Freiburg)

Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology,Immunology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1186/s12974-015-0473-7

Reference62 articles.

1. Forrest CM, Khalil OS, Pisar M, Smith RA, Darlington LG, Stone TW. Prenatal activation of toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring. Mol Brain. 2012;5:22.

2. Reisinger S, Khan D, Kong E, Berger A, Pollak A, Pollak DD. The poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery. Pharmacol Ther. 2015;149:213–26.

3. Kariko K, Ni H, Capodici J, Lamphier M, Weissman D. mRNA is an endogenous ligand for toll-like receptor 3. J Biol Chem. 2004;279:12542–50.

4. Lundberg AM, Drexler SK, Monaco C, Williams LM, Sacre SM, Feldmann M, et al. Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems. Blood. 2007;110:3245–52.

5. Olson JK, Miller SD. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol. 2004;173:3916–24.

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