[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis-Reference-Cited by-同舟云学术

[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis

Published:2018-02-22 Issue:1 Volume:15 Page:
ISSN:1742-2094
Container-title:Journal of Neuroinflammation
language:en
Short-container-title:J Neuroinflammation

Author:

Hoehne Aileen,James Michelle L.,Alam Israt S.,Ronald John A.,Schneider Bernadette,D’Souza Aloma,Witney Timothy H.,Andrews Lauren E.,Cropper Haley C.,Behera Deepak,Gowrishankar Gayatri,Ding Zhaoqing,Wyss-Coray Tony,Chin Frederick T.,Biswal Sandip,Gambhir Sanjiv S.

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology,Immunology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1186/s12974-018-1080-1.pdf

Reference29 articles.

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2. Gilgun-Sherki Y, Melamed E, Offen D. The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy. J Neurol. 2004;251:261–8.

3. Conrad M, Sato H. The oxidative stress-inducible cystine/glutamate antiporter, system x c-: cystine supplier and beyond. Amino Acids. 2012;42:231–46.

4. Domercq M, Sánchez-Gómez MV, Sherwin C, Etxebarria E, Fern R, Matute C. System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes. J Immunol. 2007;178:6549–56.

5. Kostic M, Zivkovic N, Stojanovic I. Multiple sclerosis and glutamate excitotoxicity. Rev Neurosci. 2013;24:71–88.

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