Semaphorin4A causes loss of mature oligodendrocytes and demyelination in vivo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology,Immunology,General Neuroscience
Link
http://link.springer.com/content/pdf/10.1186/s12974-019-1420-9.pdf
Reference37 articles.
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2. Love S. Demyelinating diseases. J Clin Pathol. 2006;59:1151–9.
3. Kumanogoh A, Marukawa S, Suzuki K, Takegahara N, Watanabe C. Ch’ng E, et al. Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature. 2002;419:629–33.
4. Leitner DF, Todorich B, Zhang X, Connor JR. Semaphorin4A is cytotoxic to oligodendrocytes and is elevated in microglia and multiple sclerosis. ASN Neuro. 2015;7:1–13.
5. Chiou B, Lucassen E, Sather M, Kallianpur A, Connor J. Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: a novel neuro-immune axis. Glia. 2018;66:1317–30.
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