Author:
Zhao Huajian,Zheng Yiming,Meng Lingchao,Yu Meng,Zhang Wei,Lv He,Wang Zhaoxia,Hao Hongjun,Yuan Yun
Abstract
Abstract
Background
Cranial nerve involvement is not commonly encountered in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP); this is especially true for involvement of the hypoglossal nerve. Neither Beevor's sign nor its inverted form has previously been described in CIDP.
Case presentation
A 28-year-old man presented with distal-predominant limb weakness and numbness at the age of 18. A diagnosis of CIDP was made, which was confirmed by electrodiagnostic evidence of demyelination. He responded well to intravenous immunoglobulin and glucocorticoid treatment and achieved remission for 5 years. However, the same symptoms relapsed at the age of 28 and lasted for 10 months. On examination, in addition to limb sensory impairment and muscle weakness, mild bilateral facial paresis, tongue atrophy and fasciculations, and inverted Beevor's sign were also observed. A brief literature review of cranial nerve involvements in CIDP and Beevor's sign or its inverted form were also performed.
Conclusions
Cranial nerves may be affected in patients with CIDP. Facial palsy is most frequently present, while hypoglossal nerve involvement is rare. Inverted Beevor's sign can appear in CIDP patients.
Publisher
Springer Science and Business Media LLC
Subject
Clinical Neurology,General Medicine
Cited by
1 articles.
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1. The Hypoglossal Nerve;Seminars in Ultrasound, CT and MRI;2023-04