Author:
Lidetu Tadios,Zewdu Dagmawit
Abstract
Abstract
Background
A post stroke seizure is a period of neurological dysfunction caused by abnormal neuronal activity. Seizures after a stroke have an impact on patients' lives and increase mortality in stroke patients. It also has a negative impact on the prognosis of stroke. However, there is a scarcity of literature in Ethiopia on the occurrence of post-stroke seizures. Therefore, this study aimed to assess the incidence and predictors of post-stroke seizure at Felege Hiwot compressive specialized hospital, North West Ethiopia.
Methods
An institution-based retrospective follow-up study was carried out at Felege Hiwot Compressive Specialized Hospital, North West Ethiopia from July 1, 2017 to June 30, 2021. The records of 568 stroke patients were reviewed using a random sample method. To find predictors of post-stroke seizures, we applied the log-binomial regression model.
Result
The incidence of post-stroke seizures was 22.18%( 95% CI 18.83%—25.83%). Older age group (ARR = 2.49, 95% CI 1.33–4.69), hemorrhagic stroke (ARR = 1.99, 95% CI 1.25–3.17), surgical intervention (ARR = 1.85, 95% CI 1.22–2.81), and tramadol medication (ARR = 1.85, 95% CI 1.22–2.81) were found to be predictors of post stroke seizure.
Conclusion
This study revealed that the incidence of post stroke seizure was high and older age, haemorrhagic type of stroke, surgical management, and use of tramadol anti-pain medication are risk factors for post-stroke seizures. Therefore, health care professionals must pay special attention and provide clinical care to patients who have risk factors for post-stroke seizure.
Publisher
Springer Science and Business Media LLC
Subject
Neurology (clinical),General Medicine
Reference36 articles.
1. Huff J, Seizure M. StatPearls [Internet][Updated 20 Mar 2020] 2020 Available from: Treasure Island (FL): StatPearls Publishing https://www.ncbi.nlm.nih.gov/books/NBK430765. 2020.
2. Zelano J, Holtkamp M, Agarwal N, Lattanzi S, Trinka E, Brigo F. How to diagnose and treat post-stroke seizures and epilepsy. Epileptic Disord. 2020;22(3):252–63.
3. Doria JW, Forgacs PB. Incidence, implications, and management of seizures following ischemic and hemorrhagic stroke. Curr Neurol Neurosci Rep. 2019;19(7):1–8.
4. Lucci FR, Alet M, Ameriso SF. Post-stroke epilepsy. Medicina. 2018;78(2):86–90.
5. Xu MY. Poststroke seizure: optimising its management. Stroke and vascular neurology. 2019;4(1):48–56.