Author:
Veenith Tonny,Goon Serena SH,Burnstein Rowan M
Abstract
Abstract
Head injury is common, sometimes requires intensive care unit admission, and is associated with significant mortality and morbidity. A gap still remains in the understanding of the molecular mechanism of this condition. This review is aimed at providing a general overview of the molecular mechanisms involved in traumatic brain injury to a busy clinician. It will encompass the pathophysiology in traumatic brain injury including apoptosis, the role of molecules and genes, and a brief mention of possible pharmacological therapies.
Publisher
Springer Science and Business Media LLC
Subject
Emergency Medicine,Surgery
Reference60 articles.
1. Sultan HY, Boyle A, Pereira M, Antoun N, Maimaris C: Application of the Canadian CT head rules in managing minor head injuries in a UK emergency department: implications for the implementation of the NICE guidelines. Emerg Med J. 2004, 21 (4): 420-5. 10.1136/emj.2003.011353.
2. Fleminger S, Ponsford J: Long term outcome after traumatic brain injury (Editorial). BMJ. 2005, 331: 1419-20. 10.1136/bmj.331.7530.1419.
3. Langlois JA, Rutland-Brown W, Thomas KE: Traumatic brain injury in the United States: emergency department visits, hospitalizations, and deaths. 2004, Atlanta (GA): Centers for Disease Control and Prevention. National Center for Injury Prevention and Control
4. Burdens of disease a discussion document. 1996, London: Department of Health, NHS Executive
5. Perel P, Edwards P, Wentz R, Roberts I: Systematic review of prognostic models in traumatic brain injury. BMC Med Inform Decis Mak. 2006, 14 (6): 38-10.1186/1472-6947-6-38.
Cited by
34 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献