A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide reductase-Reference-Cited by-同舟云学术

A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide reductase

Published:2015-10-13 Issue:1 Volume:8 Page:
ISSN:1756-8935
Container-title:Epigenetics & Chromatin
language:en
Short-container-title:Epigenetics & Chromatin

Author:

Minkovsky Alissa,Sahakyan Anna,Bonora Giancarlo,Damoiseaux Robert,Dimitrova Elizabeth,Rubbi Liudmilla,Pellegrini Matteo,Radu Caius G.,Plath Kathrin

Funder

National Institutes of Health

California Institute for Regenerative Medicine

National Institute on Aging

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology

Link

http://link.springer.com/content/pdf/10.1186/s13072-015-0034-4.pdf

Reference58 articles.

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2. Lee JT. Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol. 2011;12:815–26.

3. Pollex T, Heard E. Recent advances in X-chromosome inactivation research. Curr Opin Cell Biol. 2012;24:825–32.

4. Costanzi C, Pehrson JR. Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals. Nature. 1998;393:599–601.

5. Gendrel A-V, Apedaile A, Coker H, Termanis A, Zvetkova I, Godwin J, Tang YA, Huntley D, Montana G, Taylor S, Giannoulatou E, Heard E, Stancheva I, Brockdorff N. Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome. Dev Cell. 2012;23:265–79.

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