Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693-Reference-Cited by-同舟云学术

Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693

Published:2010-07-06 Issue:1 Volume:11 Page:
ISSN:1471-2164
Container-title:BMC Genomics
language:en
Short-container-title:BMC Genomics

Author:

Kumar Rakesh,Blakemore Stephen J,Ellis Catherine E,Petricoin Emanuel F,Pratt Dexter,Macoritto Michael,Matthews Andrea L,Loureiro Joseph J,Elliston Keith

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Biotechnology

Link

http://link.springer.com/content/pdf/10.1186/1471-2164-11-419.pdf

Reference42 articles.

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3. Bellacosa A, Kumar CC, Di Cristofano A, Testa JR: Activation of AKT kinases in cancer: implications for therapeutic targeting. Adv Cancer Res. 2005, 94: 29-86. 10.1016/S0065-230X(05)94002-5.

4. Carpten JD, Faber AL, Horn C, Donoho GP, Briggs SL, Robbins CM, Hostetter G, Boguslawski S, Moses TY, Savage S: A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature. 2007, 448: 439-444. 10.1038/nature05933.

5. Cheng JQ, Lindsley CW, Cheng GZ, Yang H, Nicosia SV: The Akt/PKB pathway: molecular target for cancer drug discovery. Oncogene. 2005, 24: 7482-7492. 10.1038/sj.onc.1209088.

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