Author:
Hussen Bashdar Mahmud,Faraj Goran Sedeeq Hama,Rasul Mohammad Fatih,Hidayat Hazha Jamal,Salihi Abbas,Baniahmad Aria,Taheri Mohammad,Ghafouri-Frad Soudeh
Abstract
AbstractExosomes are naturally occurring nanosized particles that aid intercellular communication by transmitting biological information between cells. Exosomes have therapeutic efficacy that can transfer their contents between cells as natural carriers. In addition, the exosomal contents delivered to the recipient pathological cells significantly inhibit cancer progression. However, exosome-based tumor treatments are inadequately precise or successful, and various challenges should be adequately overcome. Here, we discuss the significant challenges that exosomes face as drug carriers used for therapeutic targets and strategies for overcoming these challenges in order to promote this new incoming drug carrier further and improve future clinical outcomes. We also present techniques for overcoming these challenges.
Funder
Friedrich-Schiller-Universität Jena
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Oncology
Cited by
20 articles.
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