A review on the role of MEG8 lncRNA in human disorders-Reference-Cited by-同舟云学术

A review on the role of MEG8 lncRNA in human disorders

Published:2022-09-16 Issue:1 Volume:22 Page:
ISSN:1475-2867
Container-title:Cancer Cell International
language:en
Short-container-title:Cancer Cell Int

Author:

Ghafouri-Fard Soudeh,Khoshbakht Tayyebeh,Hussen Bashdar Mahmud,Taheri Mohammad,Shojaei Seyedpouzhia

Abstract

AbstractMaternally expressed 8 (MEG8) is a long non-coding RNA which is expressed in the nucleus. It is highly expressed in adrenal, placenta and brain. Recent studies have shown contribution of MEG8 in different disorders ranging from neoplastic ones to diabetic nephropathy, atherosclerosis, ischemic stroke, trophoblast dysfunction and abortion, Henoch-Schonlein purpura and osteoarthritis. It has an oncogenic role in the development of lung, pancreatic and liver cancer. In the current review, we summarize the role of this lncRNA in mentioned disorders, based on the evidence obtained from in vitro, in vivo and human studies.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Oncology

Link

https://link.springer.com/content/pdf/10.1186/s12935-022-02705-9.pdf

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