Klüver–Bucy syndrome secondary to a nondominant middle cerebral artery ischemic stroke: a case report and review of the literature

Author:

Al-Attas Alawi Aqel,Aldayel Abdulrahman Yousef,Aloufi Tareq Hamad,Biary Nabil

Abstract

Abstract Background Klüver–Bucy syndrome is a rare and complex neurobehavioral cluster that occurs in humans and results from a temporal lobe lesion. It can be associated with a variety of causes. Stroke is a rarely reported cause of this syndrome. Case presentation In this report, we present the case of a 68-year-old Saudi male who developed Klüver–Bucy syndrome subsequent to a nondominant middle cerebral artery ischemic stroke involving right temporal lobe. The patient manifested most of the Klüver–Bucy syndrome clinical features, including hypersexuality, hyperphagia, hyperorality, and visual hypermetamorphosis (excessive tendency to react to every visual stimulation with a tendency to touch every such stimulus). These neurobehavioral manifestations improved after he was started on treatment. Conclusions The clinical course, anatomical association relying on pathophysiology, and potential treatment have all been deliberated in regard to the rare occurrence of Klüver–Bucy syndrome resulting from temporal lobe pathology.

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Reference28 articles.

1. Garrett KD, Irani F, Libon DJ, Swenson R, Wambach DM. Klüver-Bucy syndrome. In: Kreutzer JS, DeLuca J, Caplan B, editors. Encyclopedia of clinical neuropsychology. New York, NY: Springer; 2011. p. 1405–10.

2. Klüver H, Bucy P. Preliminary analysis of functions of the temporal lobes in man. Arch J Comp Neurol. 1939;42:979–1000.

3. Bucy PC, Klüver H. An anatomical investigation of the temporal lobe in the monkey (Macacamulatta). J Comp Neurol. 1955;103:151–251.

4. M Das J, Siddiqui W. Kluver Bucy syndrome. [Updated 2019 Jun 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019.

5. Kar SK, Jaiswal A, Panda AK. A case report of partial Kluver-Bucy syndrome with anterior opercular syndrome in childhood: a sequel of limbic encephalitis. J Indian Assoc Child Adolesc Ment Health. 2013;9:80–8.

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