Author:
Tehranian Afsaneh,Ghahghaei-Nezamabadi Akram,Seifollahi Akram,Kasraei Sara,Dehghani-Nejad Hamideh,Maleki-Hajiagha Arezoo
Abstract
Abstract
Background
Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols.
Case presentation
We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis.
Conclusion
The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival.
Publisher
Springer Science and Business Media LLC
Reference13 articles.
1. Chen R-J, Chen K-Y, Chang T-C, Sheu B-C, Chow S-N, Huang S-C. Prognosis and treatment of squamous cell carcinoma from a mature cystic teratoma of the ovary. J Formos Med Assoc. 2008;107(11):857–68.
2. Sakuma M, Otsuki T, Yoshinaga K, Utsunomiya H, Nagase S, Takano T, et al. Malignant transformation arising from mature cystic teratoma of the ovary: a retrospective study of 20 cases. Int J Gynecol Cancer. 2010;20(5):766–71.
3. Rathore R, Sharma S, Agarwal S. Malignant transformation in mature cystic teratoma of the ovary: a retrospective study of eight cases and review of literature. Przeglad Menopauzalny. 2018;17(2):63.
4. Goudeli C, Varytimiadi A, Koufopoulos N, Syrios J, Terzakis E. An ovarian mature cystic teratoma evolving in squamous cell carcinoma: a case report and review of the literature. Gynecol Oncol Rep. 2017;19:27–30.
5. Kikkawa F, Nawa A, Tamakoshi K, Ishikawa H, Kuzuya K, Suganuma N, et al. Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary. Cancer. 1998;82(11):2249–55.
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