Author:
Hanyu Shota,Sugita Naoko,Matsuda Miyuki,Murai Toshiya,Fujiwara Hironobu
Abstract
Abstract
Background
Lithium carbonate is widely used as a first-line therapeutic agent for the depressive and manic phases of bipolar disorder. Although limb tremors and hypothyroidism are well-known side effects of lithium carbonate, other rare adverse reactions can also occur.
Case presentation
A 53-year-old Japanese woman diagnosed with lithium intoxication developed dysgeusia and glossalgia during treatment with lithium carbonate. She also showed symptoms of a swaying gait, finger tremors, and dysarthria. All of these symptoms subsided when her blood lithium concentration was reduced to a level below that which induces intoxication.
Conclusions
We present a rare case of lithium carbonate–induced dysgeusia accompanied by glossalgia. Early detection of these symptoms is important in clinical settings because they can be overlooked until patients lose their appetite, which severely impairs their quality of life.
Publisher
Springer Science and Business Media LLC
Reference29 articles.
1. McKnight RF, Adida M, Budge K, Stockton S, Goodwin GM, Geddes JR. Lithium toxicity profile: a systematic review and meta-analysis. Lancet. 2012;379:721–49.
2. Nolen WA, Weisler RH. The association of the effect of lithium in the maintenance treatment of bipolar disorder with lithium plasma levels: a post hoc analysis of a double-blind study comparing switching to lithium or placebo in patients who responded to quetiapine (Trial 144). Bipolar Disord. 2013;15:100–9.
3. Ott M, Stegmayr B, Salander RE, Werneke U. Lithium intoxication: incidence, clinical course and renal function – a population-based retrospective cohort study. J Psychopharmacol. 2016;30:1008–19.
4. Haussmann R, Bauer M, von Bonin S, Grof P, Lewitzka U. Treatment of lithium intoxication: facing the need for evidence. Int J Bipolar Disord. 2015;3:23.
5. Yukihiro M, Hideyuki T, Koichi K, Fumihiro M, Katumi M, Keiko A, et al. Clinical statistics of patients with lingual abnormalities including glossalgia – clinical characteristics of glossodynia [in Japanese]. Jpn J Orofac Pain. 2012;5:27–35.
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献