Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae-Reference-Cited by-同舟云学术

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Published:2019-02-01 Issue:1 Volume:18 Page:
ISSN:1475-2859
Container-title:Microbial Cell Factories
language:en
Short-container-title:Microb Cell Fact

Author:

Bergman Alexandra,Hellgren John,Moritz Thomas,Siewers Verena,Nielsen Jens,Chen Yun

Funder

Novo Nordisk Fonden

Knut och Alice Wallenbergs Stiftelse

Stiftelsen för Strategisk Forskning

Svenska Forskningsrådet Formas

Carl Tryggers Stiftelse för Vetenskaplig Forskning

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://link.springer.com/content/pdf/10.1186/s12934-019-1072-6.pdf

Reference35 articles.

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3. Feng XY, Lian JZ, Zhao HM. Metabolic engineering of Saccharomyces cerevisiae to improve 1-hexadecanol production. Metab Eng. 2015;27:10–9.

4. Zhou YJJ, Buijs NA, Zhu ZW, Qin JF, Siewers V, Nielsen J. Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories. Nat Commun. 2016;7:11709.

5. Rodriguez S, Denby CM, Van Vu T, Baidoo EE, Wang G, Keasling JD. ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae. Microb Cell Fact. 2016;15:48.

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