Increased radiosensitivity and radiothermosensitivity of human pancreatic MIAPaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitorNVP-HSP990

Author:

Milanović Dušan,Firat Elke,Grosu Anca Ligia,Niedermann Gabriele

Publisher

Springer Science and Business Media LLC

Subject

Radiology Nuclear Medicine and imaging,Oncology

Reference36 articles.

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3. Trepel J, Mollapour M, Giaccone G, Neckers L: Targeting the dynamic HSP90 complex in cancer. Nat Rev Cancer 2010, 10: 537-549.

4. Chautard E, Loubeau G, Tchirkov A, Chassagne J, Vermot-Desroches C, Morel L, Verrelle P: Akt signaling pathway: a target for radiosensitizing human malignantglioma. Neuro Oncol 2010, 12: 434-443.

5. Pietras RJ, Poen JC, Gallardo D, Wongvipat PN, Lee HJ, Slamon DJ: Monoclonal antibody to HER-2/neureceptor modulates repair ofradiation-induced DNA damage and enhances radiosensitivity of human breastcancer cells overexpressing this oncogene. Cancer Res 1999, 59: 1347-1355.

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