Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague–Dawley rats

Author:

Seiffert Joanna,Buckley Alison,Leo Bey,Martin Nicholas G.,Zhu Jie,Dai Ranran,Hussain Farhana,Guo Chang,Warren James,Hodgson Alan,Gong Jicheng,Ryan Mary P.,Zhang Junfeng (Jim),Porter Alexandra,Tetley Terry D.,Gow Andrew,Smith Rachel,Chung Kian FanORCID

Funder

US National Institute for Environmental Health Sciences

Natural Environment Research Council

Publisher

Springer Science and Business Media LLC

Reference41 articles.

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2. Takenaka S, Karg E, Roth C, Schulz H, Ziesenis A, Heinzmann U, Schramel P, Heyder J. Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats. EnvironHealth Perspect. 2001;109 Suppl 4:547–51.

3. Hyun JS, Lee BS, Ryu HY, Sung JH, Chung KH, Yu IJ. Effects of repeated silver nanoparticles exposure on the histological structure and mucins of nasal respiratory mucosa in rats. Toxicol Lett. 2008;182:24–8.

4. Anderson DS, Silva RM, Lee D, Edwards PC, Sharmah A, Guo T, Pinkerton KE, Van Winkle LS. Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition. Nanotoxicology. 2014;9:1–12.

5. Braakhuis HM, Cassee FR, Fokkens PH, de la Fonteyne LJ, Oomen AG, Krystek P, de Jong WH, van Loveren H, Park MV. Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study. Nanotoxicology. 2015;10:1–11.

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