Abstract
Abstract
Background
In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurring. The aim of this study was to explore the working conceptual framework of health related quality of life (HRQL) for those living with chronic HBV through qualitative analysis.
Methods
Data were collected by in-depth telephone interviews conducted in 2019 using purposeful sampling as part of a disease understanding assessment on the HBV patient experience within the United States. A directed content analysis approach was utilized by creation of a codebook to guide the organization of data, codes were developed by review of the literature (a priori) and through line-by-line reading of a subsample of queries. All transcripts were analyzed by at least two members of the study team and intercoder reliability was assessed using Dedoose software.
Findings
A sample of 19 individuals living with chronic HBV were included within this study. Themes identified from transcripts noted the significant overlap between the reported experience of HBV and constructs within the HRQL model. The psychological impact of chronic HBV on study participants’ HRQL overall was considerable and contributed to depression, anxiety, homelessness, drug use, and incarceration.
Conclusion
Our analysis supports the hypothesis that HBV impacts HRQL and often negatively affects emotional health. Our findings suggest that it would be beneficial to include HRQL assessment in the medical management of HBV, so that interventions can focus on reducing the burden of disease and improving quality of life for those living with HBV.
Publisher
Springer Science and Business Media LLC
Subject
Health Information Management,Health Informatics
Reference29 articles.
1. WHO (2021) Global progress report on HIV, viral hepatitis and sexually transmitted infections, vol 53. WHO, Geneva
2. Wong R, Welch S et al (2021) An updated assessment of chronic hepatitis b prevalence among foreign-born persons living in the United States. Hepatology. https://doi.org/10.1002/hep.31782
3. Hepatitis B (2020) 27:1–9. http://www.who.int/mediacentre/factsheets/fs204/en
4. Lok AS, Zoulim F, Dusheiko G, Ghany MG (2017) Hepatitis B cure: from discovery to regulatory approval. J Hepatol 67(4):847–861. https://doi.org/10.1016/j.jhep.2017.05.008
5. Terrault NA, Bzowej NH, Chang KM, Hwang JP, Jonas MM, Murad MH (2016) AASLD guidelines for treatment of chronic hepatitis B. Hepatology 63(1):261–283. https://doi.org/10.1002/hep.28156
Cited by
12 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献