Abstract
Abstract
Background
Several models for educational simulation of labor and delivery were published in the literature and incorporated into a commercially available training simulator (CAE Healthcare Lucina). However, the engine of this simulator does not include a model for the clinically relevant indicators: uterine contraction amplitude and frequency, and cervical dilation. In this paper, such a model is presented for the primigravida in normal labor.
Methods
The conceptual and mathematical models represent oxytocin release by the hypothalamus, oxytocin pharmacokinetics, and oxytocin effect on uterine contractions, cervical dilation, and (positive) feedback from cervical dilation to oxytocin release by the hypothalamus.
Results
Simulation results for cervical dilation are presented, together with target data for a normal primigravida. Corresponding oxytocin concentrations and amplitude and frequency of uterine contractions are also presented.
Conclusion
An original empirical model for educational simulation of oxytocin concentration, uterine contractions, and cervical dilation in first-stage labor is presented. Simulation results for cervical dilation match target data for a normal patient. The model forms a basis for taking into account more independent variables and patient profiles and can thereby considerably expand the range of training scenarios that can be simulated.
Publisher
Springer Science and Business Media LLC
Reference11 articles.
1. Bastos LF, Lobo MF, van Meurs WL, Ayres-de-Campos D. An intrauterine pressure generator for educational simulation of labour and delivery. Med Eng Phys. 2010;32:740–5.
2. Bastos LF, van Meurs W, Ayres-de-Campos D. A model for educational simulation of the evolution of uterine contractions during labor. Comput Methods Prog Biomed. 2012;107:242–7.
3. Lobo MF, Bastos LF, van Meurs WL, Ayres-de-Campos D. A model for educational simulation of the effect of oxytocin on uterine contractions. Med Eng Phys. 2013;35:524–31.
4. Childbirth simulator. https://caehealthcare.com/patient-simulation/lucina. Accessed 8 June 2017.
5. Marieb EN, Hoehn K. Pregnancy and Human Development. In: Human anatomy and physiology. 10th ed: Pearson Education, Limited; 2015. p. 1116–7.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献