Computational determination of hERG-related cardiotoxicity of drug candidates-Reference-Cited by-同舟云学术

Computational determination of hERG-related cardiotoxicity of drug candidates

Published:2019-05 Issue:S10 Volume:20 Page:
ISSN:1471-2105
Container-title:BMC Bioinformatics
language:en
Short-container-title:BMC Bioinformatics

Author:

Lee Hyang-Mi,Yu Myeong-Sang,Kazmi Sayada Reemsha,Oh Seong Yun,Rhee Ki-Hyeong,Bae Myung-Ae,Lee Byung Ho,Shin Dae-Seop,Oh Kwang-Seok,Ceong Hyithaek,Lee Donghyun,Na Dokyun

Publisher

Springer Science and Business Media LLC

Subject

Applied Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Structural Biology

Link

http://link.springer.com/content/pdf/10.1186/s12859-019-2814-5.pdf

Reference33 articles.

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3. Laverty H, Benson C, Cartwright E, Cross M, Garland C, Hammond T, et al. How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines? Br J Pharmacol. 2011;163(4):675–93.

4. Polak S, Wisniowska B, Brandys J. Collation, assessment and analysis of literature in vitro data on hERG receptor blocking potency for subsequent modeling of drugs' cardiotoxic properties. J Appl Toxicol. 2009;29(3):183–206.

5. Kratz JM, Schuster D, Edtbauer M, Saxena P, Mair CE, Kirchebner J, et al. Experimentally validated hERG pharmacophore models as cardiotoxicity prediction tools. J Chem Inf Model. 2014;54(10):2887–901.

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