Single-cell gene expression analysis reveals β-cell dysfunction and deficit mechanisms in type 2 diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Applied Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Structural Biology
Link
http://link.springer.com/content/pdf/10.1186/s12859-018-2519-1.pdf
Reference58 articles.
1. Organization WH, et al. Global Report on Diabetes. France: World Health Organization; 2016.
2. Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest. 1999; 104(6):787–94.
3. Bergman RN, Finegood D, Kahn S. The evolution of β-cell dysfunction and insulin resistance in type 2 diabetes. Eur J Clin Invest. 2002; 32:35–45.
4. Kahn S. The importance of β-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab. 2001; 86(9):4047–58.
5. Rhodes CJ. Type 2 diabetes-a matter of ß-cell life and death?. Sci. 2005; 307(5708):380–4.
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