How can functional annotations be derived from profiles of phenotypic annotations?-Reference-Cited by-同舟云学术

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How can functional annotations be derived from profiles of phenotypic annotations?

Published:2017-02-10 Issue:1 Volume:18 Page:
ISSN:1471-2105
Container-title:BMC Bioinformatics
language:en
Short-container-title:BMC Bioinformatics

Author:

Serrano-Solano Beatriz,Díaz Ramos Antonio,Hériché Jean-Karim,Ranea Juan A. G.

Funder

Seventh Framework Programme

Secretaría de Estado de Investigación, Desarrollo e Innovación

Agencia de Innovación y Desarrollo de Andalucía

Instituto de Salud Carlos III

Publisher

Springer Science and Business Media LLC

Subject

Applied Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Structural Biology

Link

http://link.springer.com/content/pdf/10.1186/s12859-017-1503-5.pdf

Reference41 articles.

1. Lock JG, Strömblad S. Systems microscopy: an emerging strategy for the life sciences. Exp Cell Res. 2010; 316(8):1438–44. doi: 10.1016/j.yexcr.2010.04.001 .

2. Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MHA, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature. 2010; 464(7289):721–7. doi: 10.1038/nature08869 .

3. Fuchs F, Pau G, Kranz D, Sklyar O, Budjan C, Steinbrink S, Horn T, Pedal A, Huber W, Boutros M. Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol. 2010; 6(370):370. doi: 10.1038/msb.2010.25 .

4. Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R. Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol. 2012; 14(7):764–74. doi: 10.1038/ncb2510 .

5. Hoehndorf R, Harris MA, Herre H, Rustici G, Gkoutos GV. Semantic integration of physiology phenotypes with an application to the Cellular Phenotype Ontology. Bioinforma (Oxford, England). 2012; 28(13):1783–9. doi: 10.1093/bioinformatics/bts250 .

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