Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition

Author:

Zhang Haiyu,Cohen Adam L,Krishnakumar Sujatha,Wapnir Irene L,Veeriah Selvaraju,Deng Glenn,Coram Marc A,Piskun Caroline M,Longacre Teri A,Herrler Michael,Frimannsson Daniel O,Telli Melinda L,Dirbas Frederick M,Matin AC,Dairkee Shanaz H,Larijani Banafshe,Glinsky Gennadi V,Bild Andrea H,Jeffrey Stefanie S

Publisher

Springer Science and Business Media LLC

Reference76 articles.

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2. Badve S, Dabbs DJ, Schnitt SJ, Baehner FL, Decker T, Eusebi V, Fox SB, Ichihara S, Jacquemier J, Lakhani SR, Palacios J, Rakha EA, Richardson AL, Schmitt FC, Tan PH, Tse GM, Weigelt B, Ellis IO, Reis-Filho JS: Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists. Mod Pathol. 2011, 24: 157-167. 10.1038/modpathol.2010.200.

3. Kyndi M, Sørensen FB, Knudsen H, Overgaard M, Nielsen HM, Overgaard J, Danish Breast Cancer Cooperative Group: Estrogen receptor, progesterone receptor, HER-2, and response to postmastectomy radiotherapy in high-risk breast cancer: the Danish Breast Cancer Cooperative Group. J Clin Oncol. 2008, 26: 1419-1426. 10.1200/JCO.2007.14.5565.

4. Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D: Molecular portraits of human breast tumours. Nature. 2000, 406: 747-752. 10.1038/35021093.

5. Prat A, Adamo B, Cheang MC, Anders CK, Carey LA, Perou CM: Molecular characterization of basal-like and non-basal-like triple-negative breast cancer. Oncologist. 2013, 18: 123-133. 10.1634/theoncologist.2012-0397.

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