Funder
NIHR Southampton Biomedical Research Centre
Publisher
Springer Science and Business Media LLC
Reference18 articles.
1. Pollard AJ, Savulescu J, Oxford J, Hill AV, Levine MM, Lewis DJ, et al. Human microbial challenge: the ultimate animal model. Lancet Infect Dis. 2012;12:903–5.
2. WHO Expert Committee on Biological Standardization. Human challenge trials for vaccine development: regulatory considerations. WHO Technical Report Series, No. 1004, 2017. Accessed May 2020. Available from:
https://www.who.int/biologicals/expert_committee/WHO_TRS_1004_web_Annex_10.pdf?ua=1
.
3. Thanh Le T, Andreadakis Z, Kumar A, Gomez Roman R, Tollefsen S, Saville M, et al. The COVID-19 vaccine development landscape. Nat Rev Drug Discov. 2020;19:305–6.
4. Pronker ES, Weenen TC, Commandeur H, Claassen EH, Osterhaus AD. Risk in vaccine research and development quantified. PLoS One. 2013;8:e57755.
5. Amanat F, Krammer F. SARS-CoV-2 vaccines: status report. Immunity. 2020;52:583–9.