Genetic Inactivation and Pharmacological Blockade of Sigma-1 Receptors Prevent Paclitaxel-Induced Sensory-Nerve Mitochondrial Abnormalities and Neuropathic Pain in Mice

Author:

Nieto Francisco R12,Cendán Cruz M1,Cañizares Francisco J3,Cubero María A3,Vela José M4,Fernández-Segura Eduardo3,Baeyens José M

Affiliation:

1. Department of Pharmacology, Biomedical Research Centre and Institute of Neuroscience, University of Granada, 18012 Granada, Spain

2. Current address: Wolfson Centre for Age-Related Diseases, King's College London, Wolfson Wing, Hodgkin Building, SE1 1UL London, UK

3. Department of Histology, Biomedical Research Centre and Institute of Neuroscience, University of Granada, 18012 Granada, Spain

4. Esteve, Drug Discovery and Preclinical Development, Parc Científic de Barcelona, Carrer Baldiri Reixac, 4-8, 08028 Barcelona, Spain

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Cellular and Molecular Neuroscience,Molecular Medicine

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