Discovery of a natural small-molecule compound that suppresses tumor EMT, stemness and metastasis by inhibiting TGFβ/BMP signaling in triple-negative breast cancer-Reference-Cited by-同舟云学术

Discovery of a natural small-molecule compound that suppresses tumor EMT, stemness and metastasis by inhibiting TGFβ/BMP signaling in triple-negative breast cancer

Published:2019-03-21 Issue:1 Volume:38 Page:
ISSN:1756-9966
Container-title:Journal of Experimental & Clinical Cancer Research
language:en
Short-container-title:J Exp Clin Cancer Res

Author:

Di Lei,Liu Li-Juan,Yan Yong-Ming,Fu Rong,Li Yi,Xu Ying,Cheng Yong-Xian,Wu Zhao-Qiu

Funder

National Natural Science Foundation of China

National Natural Science Fund for Distinguished Young Scholars

Jiangsu Provincial Natural Science Fund for Distinguished Young Scholars

Jiangsu Provincial Natural Science Fund for Young Scholars

State Key Laboratory of Natural Medicines of China Pharmaceutical University

Shenzhen Government’s Plan of Science and Technology

“Double First-Class” University project

Collaborative Innovation Center of Major Machine Manufacturing in Liaoning

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://link.springer.com/content/pdf/10.1186/s13046-019-1130-2.pdf

Reference39 articles.

1. Akhurst RJ, Hata A. Targeting the TGF-beta signalling pathway in disease. Nat Rev Drug Discov. 2012;11:790–811.

2. Massague J. TGF-beta signalling in context. Nat Rev Mol Cell Biol. 2012;13:616–30.

3. Pickup M, Novitskiy S, Moses HL. The roles of TGF-beta in the tumour microenvironment. Nat Rev Cancer. 2013;13:788–99.

4. Schmierer B, Hill CS. TGF-beta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol. 2007;8:970–82.

5. Liu IM, Schilling SH, Knouse KA, Choy L, Derynck R, Wang XF. TGF-beta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGF-beta switch. EMBO J. 2009;28:88–98.

Cited by 35 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Elemental detection and mapping of rat bone matrix induced by chemoradiotherapy with confocal micro-XRF;2024-09-11

2. Upregulated bone morphogenetic protein 8A (BMP8A) in triple negative breast cancer (TNBC) and its involvement in the bone metastasis;Frontiers in Cell and Developmental Biology;2024-07-19

3. Structural Optimization, Anti‐TNBC Activities Evaluation, and Molecular Docking of an Indolone Derivative from Periplaneta americana;ChemistrySelect;2024-04-23

4. Elemental detection and mapping of rat bone matrix induced by chemoradiotherapy with confocal μ-XRF;2024-04-10

5. Aspongopyrimidine A, a N-Peralkylated Histidine Zwitterion from Aspongopus chinensis against Alzheimer’s Disease Targeting MAPRE3;Organic Letters;2024-02-12