Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition

Author:

Lee Yong Sun,Lee Chung Hee,Bae Jun Tae,Nam Kyung Tak,Moon Dae Bong,Hwang Ok Kyung,Choi Jeong Soon,Kim Tae Hoon,Jun Hyoung Ok,Jung Young Suk,Hwang Dae Yeon,Han Sang-Bae,Yoon Do Young,Hong Jin Tae

Funder

National Research Foundation of korea

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference91 articles.

1. Heinhuis B, Plantinga TS, Semango G, Küsters B, Netea MG, Dinarello CA, Smit JWA, Netea-Maier RT, Joosten LAB. Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines. Carcinogenesis. 2016;37(2):197–205.

2. Kim S-H, Han S-Y, Azam T, Yoon D-Y, Dinarello CA. Interleukin-32: a cytokine and inducer of TNFα. Immunity. 2005;22(1):131–42.

3. Kempuraj D, Conti P, Vasiadi M, Alysandratos K-D, Tagen M, Kalogeromitros D, Kourelis T, Gregoriou S, Makris M, Staurianeas NG, et al. IL-32 is increased along with tryptase in lesional psoriatic skin and is up-regulated by substance P in human mast cells. Eur J Dermatol. 2010;20(6):865–7.

4. Shioya M, Nishida A, Yagi Y, Ogawa A, Tsujikawa T, Kim-Mitsuyama S, Takayanagi A, Shimizu N, Fujiyama Y, Andoh A. Epithelial overexpression of interleukin-32α in inflammatory bowel disease. Clin Exp Immunol. 2007;149(3):480–6.

5. Dinarello CA, Kim SH. IL-32, a novel cytokine with a possible role in disease. Ann Rheum Dis. 2006;65(suppl 3):iii61.

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